Continued from Creatine Benefits. It depends. If you feel great during your workouts and have good recovery times, you probably don’t need to take creatine.

However, did you know that creatine is being studied as a therapeutic intervention in a number of disease states, including (but not limited to) amyotrophic lateral sclerosis (ALS), psychiatric disorders, and Huntington’s disease (HD).

For example, animal studies show that creatine may lessen the effects of HD, a hereditary degenerative disorder of brain tissue.

In studies of individuals with a rare genetic condition known as McArdle’s disease, daily doses of creatine at 60 mg/kg of body weight seem to improve muscle function and lessen muscle fatigue.

(McArdle’s disease involves the body’s inability to produce energy from chemicals stored in muscle tissue.) In addition, muscle symptoms of individuals with muscular dystrophy and similar conditions appear to be reduced by creatine supplementation.