Prescription medications are often the treatment of choice to clear moderate to severe acne, but many people can’t tolerate the side effects. Fortunately, several new drugs are delivering results – with fewer adverse reactions.

How to clear acne (option 1) “Some dermatologists are choosing to put their acne patients on Solodyn, an extended-release minocycline. This form of the antibiotic carries less risk of headache, dizziness, and nausea,” says Hilary Baldwin, M.D., an associate clinical professor of dermatology at the State University of New York.

How to clear acne (option 2) Another new option for the yeast infection-prone (antibiotics kill the bacteria that keep yeast in check) is controlled-release doxycycline, which is not an antibiotic at all, but rather a potent anti-inflammatory that can help reduce the redness and size of pimples. [source: Shape]