Genes determine how well you respond to weight loss and exercise programs. Fat storage sites, which are genetically determined, influence how you respond to a weight-loss program and which diet works best.

A study from the Children’s Hospital in Boston showed that “apples” – people who store fat in the abdomen – lose more weight on low-carbohydrate diets (low glycemic load: 40 percent carbohydrate and 35 percent fat).

They lost 13 pounds in six months and were able to maintain the weight loss at 18 months by following a maintenance diet. Apples secrete more insulin, which makes them store more fat in the gut.

People who store fat in their abs (apples) secrete more insulin and lose weight best by following a high-protein, low-carb diet. They lose weight relatively quickly and can keep it off fairly easily.